The amount exceeds 2014, when just over 5 million tickets were sold.
The increase was also reflected in the attendance at the Panama International Film Festival, which saw attendance increase to 28,000 in 2015, 6,000 more than in 2014.
Central America in general saw an increase in attendance, said Miguel Joseph, president of the Association of Film Distributors and regional manager of United International Pictures (UIP).
In the United States and Canada, the largest film markets on the continent, ticket sales also hit a record in 2015, with a box office of 11.1 billion, 7.4 percent more than in 2014 and exceeding the previous record set in 2013 of $10.9 billion.
In Panama, the growth is attributed to both the growing economy and population in general and the increase in the number of theaters.